The Presets tab gives you the ability to quickly and easily configure color settings related to the appearance of the Helix-powered template. This includes being able to switch between pre-configured presets and custom color sets.

By default Helix Ultimate comes with 8 color presets, which allows you to choose one color style. The Preset Selector gives users the ability to quickly switch between Presets, used for whole template style, with a pre-designed color palette and style settings.
But you're not limited by only preset choices because you can enable “Custom Style” and choose there your own main colors. Notice, built-in presets will not work if this option is enabled.
For some areas you can define those also from Layout tab, separately for each Row (section). If you want to define more colors or use extra CSS3 effects you have to use custom CSS to override default font color, background colors or other elements.